Pyoderma gangrenosum in a patient with chronic granulomatous disease

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Pyoderma gangrenosum in a patient with chronic granulomatous disease

RATIONALE The simultaneous occurrence of pyoderma gangrenosum (PG) and chronic granulomatous disease (CGD) is uncommon and few cases have been reported worldwide. PATIENT CONCERNS PG is a rare, chronic, ulcerative, neutrophilic skin disease of unknown etiology that requires immunosuppressive treatment. CGD belongs to Primary Immune Deficiencies in which the main defect lies in an inability of...

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Pyoderma gangrenosum in a patient with antiphospholipid antibody negative systemic lupus erythematosus: A case report

In any description of leg ulcers in systemic lupus erythematosus (SLE), pyoderma gangrenosum (PG) earns a mention at least for its being quite rare in such patients. The causative role of aPL (antiphospholipid antibody) in dermatological manifestations of SLE is undermined by the occurrence of PG in aPL negative SLE patients. To the best of our knowledge, there are only two reports of PG in aPL...

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Intractable pyoderma gangrenosum in a Crohn's disease patient on vedolizumab

IBD: inflammatory bowel disease PG: pyoderma gangrenosum TNF-a: tumor necrosis factor alpha INTRODUCTION Pyoderma gangrenosum (PG) is a rare infiltrative neutrophilic dermatosis that characteristically presents with painful ulcers with violaceous, undermined borders on the lower extremities and less commonly presents with tender nodules or pustules. Along with erythema nodosum, PG is one of the...

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Pyoderma gangrenosum in a patient with common variable primary immunodeficiency

Pyoderma gangrenosum is a rare inflammatory skin condition that is associated with systemic inflammatory diseases. It is characterised by the presence of well-secluded, painful ulcerations, often located on the lower limbs. Similarly as in the case of acne inversa, patients' markers of the inflammatory process are elevated; including OB, C-reactive protein and leukocytosis. The aetiology takes ...

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ژورنال

عنوان ژورنال: Medicine

سال: 2017

ISSN: 0025-7974

DOI: 10.1097/md.0000000000007718